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Preheat oven to 375°F.
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Combine the cream cheese, and preserves; stir with a whisk; set aside.
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Lightly spoon flour into dry measuring cup; level with a knife.
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Combine flour, sugar, baking powder, poppy seeds, baking soda and salt in a medium bowl; make a well in center of mixture.
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Combine buttermilk, oil, egg whites, and egg; stir well with a whisk.
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Add to flour mixture, stirring just until moist.
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Spoon the batter into muffin cups coated with cooking spray; fill 1/3 full.
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Top each with about 1 tablespoons cream cheese mixture (for the large or 1 teaspoons for the small), divided the remaining batter evenly over cream cheese mixture.
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Bake at 375F for 25 minutes or until muffins spring back when touched lightly in the center. (adjust accordingly if using the mini tins).
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Remove the muffins immediately from pan,and place on wire rack.