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Preheat oven to 350 degrees.
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Cook spinach and onion together in skillet until onion is soft and spinach is completely thawed, cool slightly.
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Cut cream cheese into small cubes and place in the bottom of pie crust. Top with spinach and onion mixture.
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In a mixing bowl beat eggs. Add shredded cheese, milk, salt, black pepper and cayenne pepper.
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Pour egg mixture into crust.
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Bake at 350 degrees for 45-55 minutes or until center is set. You may have to cover it with foil for the last 10-15 minutes so the crust doesn't get too dark.
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Take out of the oven and let cool for 5-10 minutes. Serve warm.