Bring water to a boil and dissolve bouillon cubes. Remove from heat and allow to cool.
Combine ground beef, water with bouillon, bread crumbs, eggs, ketchup, onion flakes, and onion powder until completely combined.
Place meat into loaf pans, muffin tins, etc. and bake at 350 degrees until cooked through. Spread ketchup or tomato sauce over top in last 10-15 minutes if desired.