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Preheat oven to 350°F.
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Generously grease a 9x5-inch loaf pan.
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In a large mixing bowl, combine flour, baking powder, baking soda, salt and mace.
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Whisk to blend throughly.
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In the bowl of an electric mixer, combine butter and sugar.
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Beat at high speed until light and fluffy.
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Beat in egg.
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Blend in lemon rind, juice and vanilla.
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With mixer at low speed, sprinkle in dry ingredients, alternating with milk.
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Beat until well moistened.
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Gently stir in blueberries.
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Pour into prepared pan and bake for 50 to 60 minutes, covering the loaf with aluminum foil during the last 10 minutes, if necessary to prevent over browning.
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When a wooden pick inserted in the center comes out clean, transfer bread to a cooling rack.
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Let stand 10 minutes, then turn out.
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Cool completely before slicing.